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PPI Therapeutics
PPI Therapeutics

Making the undruggable Druggable

Small molecules for protein–protein interactions, a target class long treated as undruggable.

Our approach

Science. Molecules. Talent.

Rigorous research, purpose-built small molecules and a multidisciplinary team, focused on one goal: bringing protein–protein interactions within reach of medicine.

Four researchers in white coats and safety glasses working together at a bench lined with colourful flasks.

Science

We combine target selection, structural insight and translational science to find the protein–protein interactions worth drugging.

Our science
Two scientists in lab coats talking, one holding a clipboard.

Molecules

We design small molecules for selectivity at protein interfaces, the surfaces conventional drug discovery has struggled to reach.

Molecule design
Eight colleagues seated around a round wooden table with laptops in a bright meeting room.

Talent

Our multidisciplinary team brings deep expertise across discovery, chemistry and development.

Careers & culture

Our platform

Target to candidate

One integrated path, from choosing the right interaction to advancing the right molecule.

  • Discovery

    Target selection

    We use computational and structural biology to find protein–protein interactions with clear disease relevance and a credible route to small-molecule binding.

  • Chemistry

    Molecule design

    Biophysical screening, fragment-based methods and structure-based design guide molecules toward selectivity at difficult interfaces.

  • Development

    Translational strategy

    We connect discovery data to development strategy, so promising candidates advance on evidence.

  • Collaboration

    Teams and alliances

    Cross-functional teams and partnerships extend what we can do, from target validation to lead optimization.

Pipeline Draft: placeholder pending confirmation

Our programs

Program details are published here as they are confirmed.

  • PPI-101

    Target pending · Indication pending

    Stage TBC

  • PPI-202

    Target pending · Indication pending

    Stage TBC

  • PPI-303

    Target pending · Indication pending

    Stage TBC

View pipeline

By the numbers Draft: placeholder pending confirmation

Pipeline progression rate
40%
Compounds evaluated yearly
10K
Ongoing research partnerships
23+
Evidence-based decisions
100%

Latest news Draft: placeholder pending confirmation

From the lab and the company

  • Date TBC

    Science

    Headline pending

  • Date TBC

    Company

    Headline pending

  • Date TBC

    Perspectives

    Headline pending

All news

FAQ

Frequently asked questions

Answers to common questions about our science, programs and partnering.

Contact us
What is your scientific focus?

We discover and develop small-molecule medicines that modulate protein–protein interactions, a target class long considered undruggable.

How do you select targets?

We take a data-driven approach, combining structural biology, computational analysis and disease biology to find interactions that drive disease and can be reached by a small molecule.

What stages are your programs in? Draft: placeholder pending confirmation

Program stages will be published on our Pipeline page once confirmed.

How can I partner with you or learn more?

For partnership, investor or media inquiries, visit our Contact page. We welcome collaboration with academic, clinical and industry partners.

Partner with us

Accelerate tomorrow's therapies

Talk with our scientific team about partnering, licensing or investment. We welcome inquiries from collaborators, investors and scientific leaders.