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PPI Therapeutics
PPI Therapeutics

Careers at PPI Culture

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Our culture

A San Diego biotech making the undruggable druggable: small-molecule innovation at the frontier of protein–protein interactions.

A tight-knit team of scientists and innovators united by a bold vision: develop breakthrough therapies for diseases that have long evaded traditional approaches.

Values

What we hold true

  1. Bold Discovery.

    We tackle the toughest scientific challenges with courage and creativity. Where others see "undruggable," we see opportunity, and we're building the small-molecule solutions to prove it.

  2. Collaborative Spirit.

    Great science happens when brilliant minds work together. We foster an environment of open dialogue, shared goals, and mutual respect where every voice matters.

  3. Scientific Rigor.

    We are relentless in our pursuit of excellence. Data drives our decisions, and integrity guides our path from bench to bedside.

  4. Patient Focus.

    Behind every experiment is a patient waiting for hope. We never lose sight of why we do what we do.

Why PPI

Why join PPI Therapeutics

Six people gathered around a white table, smiling as they look over a large printed plan.

Ground-floor opportunity

Shape what we become

As an early-stage company, you'll have the rare chance to shape our science, culture, and future. Your contributions will have immediate and lasting impact.

A bright, empty laboratory with benches, instruments and monitors under soft pink light.

Frontier science

Make the impossible targetable

Work at the cutting edge of small-molecule drug discovery, developing innovative approaches to modulate protein–protein interactions that were once considered impossible to target. Utilize advanced biophysical screening, fragment-based methodologies, and novel platforms to transform the undruggable into tomorrow's medicines.

Seven colleagues in conversation around a glass meeting table, with coffee cups and a small plant.

Entrepreneurial

Agility meets ambition

We move fast, think big, and empower our team to take ownership. If you thrive in dynamic settings where agility meets ambition, you'll feel at home here.

A sunlit office lobby with a reception desk, potted plants and lounge seating.

San Diego biotech hub

Sun + science

Join a vibrant scientific community in one of the nation's premier biotech ecosystems, offering sunshine, collaboration, and endless opportunity.

Benefits

Support for the long road

Health & Financial Wellness

  • Comprehensive medical, dental, and vision coverage for employees and dependents
  • 401(k) with company matching (up to 5%)
  • Competitive equity participation (share in our success)
  • Life and disability insurance

Work–Life Balance

  • Generous PTO starting at 20 days annually, increasing with tenure
  • Paid holidays and sick leave in accordance with California law
  • Flexible, collaborative work environment

Growth & Development

  • Opportunity to build capabilities from the ground up
  • Exposure to end-to-end drug discovery, from target validation to lead optimization
  • A culture that values mentorship, learning, and professional advancement

Who we're looking for

We seek passionate scientists and professionals who are ready to push the boundaries of what's possible in drug discovery:

  • Curious.

    You ask "what if?" and aren't afraid to challenge the status quo.

  • Resilient.

    You see "undruggable" as a challenge, not a limitation.

  • Collaborative.

    You believe the best ideas emerge from diverse perspectives.

  • Driven.

    You're motivated by impact and inspired by innovation.

Whether you're an experienced leader or an emerging talent ready to make your mark at the frontier of protein–protein interactions, we want to hear from you.

Five colleagues in lab coats, scrubs and casual jackets standing in a circle, smiling as one of them speaks.

Life at PPI

We're more than colleagues: we're a team united by an audacious goal, making the undruggable druggable.

We celebrate wins together, support each other through challenges, and never forget that our small-molecule innovations have the potential to change lives. Our culture is built on trust, transparency, and a shared commitment to scientific excellence.

Currently hiring Draft: placeholder pending confirmation

Ready to help us make the undruggable druggable?

Explore our open positions and become part of something extraordinary at the frontier of protein–protein interactions.

Don't see your role? We're always interested in hearing from exceptional scientists and operators. Reach out via our Contact page.

A note on recruitment

PPI Therapeutics is committed to a safe and transparent hiring process. We will never request payment or sensitive personal information during recruitment. All legitimate opportunities are posted on our official website.